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THERAPEUTICALLY ACTIVE NANOMATERIALS FOR THE TREATMENT OF EYE DISEASES

are Murakami Lab’s main target. Such nanosmaterials are designed and created on the basis of a natural nanomaterial in our body, high-density lipoprotein (HDL). HDL is a ~10 nm material that consists mainly of a lipid-binding protein and a phospholipid membrane. HDL displays various biological activities during blood circulation, including cholesterol efflux capacity, anti-inflammatory activity, anti-oxidative activity. We are developing the nanomaterials with these increased activities as well as unnatural functions as eye drops.

News & Topics

  • 01/08/2021
    Event
    New lab member
    Ryosuke FUKUDA has joined as a KAKENHI "Dynamic Excition" postdoc.
  • 30/07/2021
    Work
    Meeting presentation
    Rumina SHIMA and Ryo KAWAKAMIi made an online poster presentation at the 37th Annual Meeting of the Japan Society of Drug Delivery System.
  • 01/04/2021
    News
    Research position
    Tomohiro NOBEYAMA and Ryosuke FUKUDA were selected as JSPS postdoc (DC2).
  • 05/01/2021
    Work
    Patent
    Our application regarding lipoprotein mutant eye drops for the treatment of posterior eye diseases has filed in Japan (P6818264).
  • 01/12/2020
    News
    Research grant
    The application for Grant-in-Aid for Transformative Research Areas, “Dynamic Exciton” (Project leader, Prof. Hiroshi Imahori of Kyoto Univ.) was accepted. Prof.Murakami joins as one of the PIs in this project. His research title is “Optical control of the plasma membrane functions by using dynamic exciton.
  • 16/11/2020
    Work
    Book chapter
    The book that Tomohiro and Prof.Murakami were involved in was released. What they write was Chapter 24, "Phase Separation of Lipid Membranes and Their Future." It was Tomohiro's first time writing a book.
  • 07/10/2020
    Event
    Luncheon party
    While maintaining social distance and protecting alcohol disinfection and mask, we held a welcome lunch party for Nargis(Postdoc) and Yui(B3) and Yu(B3) and Shiori(B3).
  • 29/09/2020
    Event
    PhD conferment ceremony
    The ceremony of Ph.D. degree conferment for Ryosuke and Tomohiro was held in the campus. Ryosuke and Tomohiro, congrats!
  • 19/08/2020
    Work
    Original article
    The original article regarding the optical control of membrane potential with a donor-acceptor-linked molecule was accepted for the publication in Cell. Physiol. Biochem. This work is based on the joint research with Dr. Tomohiro NUMATA (Fukuoka Univ.).
  • 05/06/2020
    Work
    Original article
    The original article of Tomohiro was accepted for the publication in Langmuir, which is already published on line. Congrats, Tomohiro!
Archive

Department of Pharmaceutical Engineering, Faculty of Engineering Toyama Prefectural University
Tatsuya Murakami Lab.

5180 Kurokawa, Imizu City, Toyama, 939-0398, Japan

Email : murakami(at))pu-toyama.ac.jp
Phone: 0766-56-7500 (within Japan),
+81-766-56-7500 (international)
Fax:0766-56-2498 (within Japan),
+81-766-56-2498 (international)