Baker's yeast Saccharomyces cerevisiae has been used in the production of food and alcoholic beverages since ancient times.
In the last century it emerged as a leading model organism for studying
molecular processes in eukaryotic cells, and it is still a very powerful
experimental system in the 21st century biology.
The remarkable features of this unicellular fungus made its astonishing
journey from the brewery and bakery to the research laboratory possible.
(from DOI: 10.1007/s 12268-022-1687-8, BENEDIKT WESTERMANN, TILL KLECKER:
Yeast Saccharomyces cerevisiae: Microbe of the Year 2022 - From Beer Brewing
to Research in the 21st Century (in German))
The tremendous body of knowledge about genetics, cell biology, and metabolism of Saccharomyces cerevisiae, as well as its long history and robustness in industrial fermentations, have made this yeast one of the most popular microbial cell factories.
Novel genetic tools have enabled the rapid construction of strains producing various platform chemicals, fuels, or pharmaceuticals.
The relevance of synthetic biology approaches, such as the construction
of fully synthetic genomes and artificial cellular compartments are not
only relevant for biotechnological applications but can also lead to new
insight into basic principles of life. (from DO1: 10.1007 / s12268-022-1704-y,
MISLAV OREB, JOANNA TRIPP: Yeast Saccharomyces cerevisiae: Microbe of
the Year - Customized yeast cells for biotechnological applications (in
German))