Research Field
Genetic engineering, Biochemistry, Molecular biology, Pharmacology、Pharmacokinetics
About Research
  • 1. Structure-function analysis of mammalian vitamin D hydroxylases.
  • 2. Metabolism of vitamin D analogues
  • 3. Structure-function analysis of mammalian cytochromes P450
  • 4. Protein engineering of St. griseolus CYP105A1 for production of 1α,      25-dihydrovitamin D3
  • 5. Molecular mechanism of vitamin D actions
  • 6. Development of novel bioluminescent sensor to detect and discriminate     between vitamin D receptor agonists and antagonists in living cells.